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(Roxitromicina):, CAS. -,. 50S,,,,. ,. ( ), 15 . 50., Cmax AUC 15. C máx 1.579) AUC T 1/2. ,,. 1/2 C máx. AUC T 1/2 (25),. ,,. . , 100, 400 135 //,. 180 //. . , .. Bordetella pertussis, catarrhalis Borrelia burgdorferi, Moraxella (Branhamella), Campylobacter coli, Campylobacter jejuni, Chlamydia trachomatis, Chlamydia psittaci, Chlamydia pneumoniae, Clostridium spp., .. Clostridium perfringens. Corynebacterium diphtheriae, Enterococcus, Gardnerella vaginalis, Staphylococcus aureus, Neisseria meningitidis, Helicobacter pylori, Pneumophilia Legionella, Listeria monocytogenes, Mycoplasma pneumoniae, Pasteurella multocida, Peptostreptococcus, Porphyromonas, Propionibacterium acnes, Rhodococcus Egui, Streptococcus spp., .. Streptococcus pneumoniae. Haemophilus influenzae, Ureaplasma urealyticum, Vibrio cholerae. Enterobacteriaceae spp. Pseudomonas spp. Acinetobacter spp. Bacteroides fragilis, Staphylococcus aureus, Fusobacterium, Mycoplasma hominis, Nocardia. -,: - (.,,,,,,,,,,), (,,,, ..,), (,,,,,), (), (,),,,). ,. . (..), (2), (.). . (). (). :,,, / (),,,. ,,. :,,,,, /,,. :,,,,,,,. :,,,,. . . AUC media (). , (). (). , (,). ,,,, QT /. ,,,. :,. . , 21). . . 150 1. ,,. ,,,. .
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